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Product Sheet

Twist Minotaur scFv Library

The Twist Minotaur scFv Library is a new synthetic antibody library that grafts ultralong HCDR3 loops from bovine antibodies into a fully human antibody framework. These elongated HCDR3 loops protrude far from the antibody surface, enabling access to occluded epitopes within protein crevices, pores, and channels. Be among the first to access the synthetic advantage for the discovery of antibodies against general and hard-to-drug targets like GPCRs, ion channels, and other membrane-bound proteins.